1l7v

About this Structure
1L7V is a 4 chains structure of sequences from Escherichia coli Out of these 2 are sequence-unique. Full crystallographic information is available from OCA.

Mechanism of Vitamin B12 Transport
The initial step constitute of coupling of substrate binding to alterations in the nucleotide-binding site. In the case of importers such as the B12 transporter, the substrate and the nucleotide-binding sites are on opposite sites of the membrane and cannot be directly coupled.

Reference
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